Denileukin diftitox
Lymphir (denileukin diftitox) is a protein pharmaceutical. Denileukin diftitox was first approved as Ontak on 1999-02-05.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Mock data
Subscribe for the real data
Subscribe for the real data
Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
Lymphir (discontinued: Ontak)
Drug Products
FDA
EMA
Reference product - 351(a)
Reference product - 351(a)
Interchangeable product - 351(k)
Interchangeable product - 351(k)
Biosimilar product - 351(k)
Biosimilar product - 351(k)
Denileukin diftitox
Tradename | Proper name | Company | Number | Date | Products |
|---|---|---|---|---|---|
| Lymphir | denileukin diftitox-cxdl | Citius Pharmaceuticals | N-761312 RX | 2024-08-07 | 1 products |
Show 1 discontinued
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| lymphir | Biologic Licensing Application | 2025-01-23 |
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
Expiration | Code | ||
|---|---|---|---|
denileukin diftitox, Ontak, Eisai, Incorporated | |||
| 2106-02-05 | Orphan excl. | ||
Patent Expiration
No data
HCPCS
No data
Clinical
Clinical Trials
52 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Lymphoma | D008223 | — | C85.9 | 1 | 6 | 2 | 3 | 1 | 13 |
| T-cell lymphoma | D016399 | — | — | 1 | 4 | 2 | 3 | 1 | 11 |
| T-cell lymphoma peripheral | D016411 | — | — | 1 | 4 | 2 | 1 | 1 | 9 |
| T-cell lymphoma cutaneous | D016410 | — | C84.A | — | 1 | 1 | 3 | 1 | 6 |
| Mycoses | D009181 | — | B35-B49 | — | — | — | 2 | — | 2 |
| Sezary syndrome | D012751 | — | C84.1 | — | — | — | 2 | — | 2 |
| Mycosis fungoides | D009182 | — | C84.0 | — | — | — | 2 | — | 2 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Recurrence | D012008 | — | — | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Melanoma | D008545 | — | — | — | 2 | — | — | — | 2 |
| Non-hodgkin lymphoma | D008228 | — | C85.9 | — | 2 | — | — | — | 2 |
| B-cell lymphoma | D016393 | — | — | — | 2 | — | — | — | 2 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | — | 1 | — | — | — | 1 |
| Leukemia | D007938 | — | C95 | — | 1 | — | — | — | 1 |
| B-cell chronic lymphocytic leukemia | D015451 | — | C91.1 | — | 1 | — | — | — | 1 |
| Lymphoid leukemia | D007945 | — | C91 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Multiple myeloma | D009101 | — | C90.0 | 1 | — | — | — | — | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | Denileukin diftitox |
| INN | denileukin diftitox |
| Description | Ontak (denileukin diftitox) is a protein pharmaceutical. Denileukin diftitox was first approved as Ontak on 1999-02-05. |
| Classification | Protein |
| Drug class | interleukins: interleukin-2 analogues and derivatives |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL1201550 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 25E79B5CTM (ChemIDplus, GSRS) |
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 1,564 documents
View more details
Safety
Black-box Warning
Black-box warning for: Lymphir
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
286 adverse events reported
View more details
© 2020-2025 Collaborative Drug Discovery Inc. (CDD) | Terms of Use